What is enclomiphene? And can it really boost testosterone?

Low testosterone affects millions of men. Recent studies show around 40% of men over 45 have testosterone levels below the optimal range. That number jumps to nearly 50% once you hit 60. 

And while Testosterone Replacement Therapy (TRT) has long been the go-to treatment, it’s not exactly a perfect fit for everyone. TRT can have some scary fertility and sexual performance side effects. 

That’s where enclomiphene might be a better fit.

Instead of using synthetic hormones, enclomiphene helps reignite your body’s own natural testosterone production. No injections. No tradeoff between feeling better and protecting your fertility. Just a simple, daily capsule designed to help you restore hormonal balance.

Let’s break down how enclomiphene works, who it’s for, and why it might be the best low T option.

What Is Enclomiphene? How Does It Work?

Enclomiphene is a selective estrogen receptor modulator (SERM) that works by stimulating the body’s own production of testosterone. 

Unlike testosterone replacement therapy (TRT), which introduces synthetic testosterone into the body, enclomiphene works by encouraging the hypothalamic-pituitary-gonadal axis (HPG axis)—the system responsible for regulating testosterone production.

Here’s how Enclomiphene works to boost testosterone:

• Blocking Estrogen Signals: Enclomiphene attaches to estrogen receptors in the brain, particularly in the hypothalamus. By doing this, it prevents estrogen from telling your brain that your testosterone levels are high enough.
  
  
• Stimulating GnRH Production: Once estrogen’s signal is blocked, the hypothalamus reacts by making more gonadotropin-releasing hormone (GnRH). GnRH is a key signal for the next step in testosterone production.
  
  
• Increasing Testosterone Production: GnRH tells the pituitary gland to release more luteinizing hormone (LH) and follicle-stimulating hormone (FSH). These hormones then go to the testes, where they stimulate the production of more testosterone.

Enclomiphene encourages the body’s natural hormonal processes to ramp up testosterone production without the need for external testosterone supplementation. 

This natural boost is important for men who want to avoid the risks of synthetic hormone use.

Unlike TRT, which can suppress your body’s natural testosterone production, enclomiphene maintains the integrity of your own hormonal systems, allowing for a more sustainable and balanced solution for low testosterone. 

Why So Many Men Are Opting For TRT Alternatives 

While TRT can boost testosterone levels and help with symptoms like fatigue and low libido, it’s far from a one-size-fits-all solution. For many men, TRT comes with a range of unwanted side effects, especially when it comes to sexual health.

Here’s what you need to know:

• Fertility Concerns & Testicular Atrophy: One of the most significant downsides of TRT is its impact on fertility. TRT can shut down your body’s natural testosterone production, causing a decline in sperm count and potentially leading to reduced fertility. This can also result in testicular atrophy—shrinkage of the testicles—due to reduced stimulation of the testes. This can be particularly concerning for men who want to have children in the future.
• Dependence on External Hormones: Since TRT introduces synthetic testosterone into your body, it can lead to long-term dependence. Once you’re on it, your body may struggle to restart natural testosterone production, meaning you’ll need to continue treatment indefinitely to maintain benefits.
  
  

This is why enclomiphene is gaining traction as a more sustainable alternative. Instead of relying on synthetic hormones, it works by stimulating your body’s own testosterone production, maintaining balance without the unwanted side effects.

For men who want to boost their testosterone naturally—without the risks of TRT—enclomiphene is proving to be a game-changer.

How Much Does Enclomiphene Raise Testosterone?

Let’s look at the research. 

Recent studies suggest that enclomiphene may significantly increase testosterone levels in men with low testosterone while preserving natural hormone function.

A randomized study published in Fertility and Sterility examined 124 men with morning testosterone levels below 250 ng/dL. 

The data shows impressive results after three months of treatment:

• 12.5 mg enclomiphene group: Testosterone increased from 217.2 ng/dL to 471.9 ng/dL (Increase of +258.8 ng/dL)
• 25 mg enclomiphene group: Testosterone increased from 209.8 ng/dL to 405.8 ng/dL (Increase of +197.3 ng/dL)
• Topical testosterone group: Testosterone increased from 210.0 ng/dL to 462.6 ng/dL (Increase of +253.7 ng/dL)
• Placebo group: Testosterone decreased from 213.7 ng/dL to 198.5 ng/dL (Decrease of -16.9 ng/dL)

Key Takeaway:

Enclomiphene may significantly boosts testosterone levels in men with low T, comparable to topical testosterone, without the need for hormone replacement.

Testosterone Boost & Fertility Concerns

What sets enclomiphene apart from traditional testosterone replacement is its mechanism of action. 

While both approaches might effectively raise testosterone to similar levels, enclomiphene simultaneously increases the body's natural testosterone production signals.

This distinction becomes critical when considering fertility implications.

The study also reported that 54% of men using topical testosterone reported reduced sperm count, compared to only 14.6% in the enclomiphene groups - a rate comparable to placebo.

These findings confirm that enclomiphene provides an effective alternative for increasing testosterone while maintaining the body's natural hormonal pathways and preserving fertility potential - a key consideration for many men seeking treatment for low testosterone.

The Takeaway: What Is Enclomiphene? How To Get It Online

Enclomiphene is a selective estrogen receptor modulator (SERM) that works, off-label, to signal your testes to increase natural testosterone production. Unlike traditional testosterone replacement therapy, enclomiphene might help restore your body's own testosterone-making capability without introducing synthetic hormones or suppressing your natural reproductive function.

Is Enclomiphene Right For You? 

Find out online. Our telemedicine platform makes it simple to connect with licensed physicians who can evaluate your symptoms and recommend an appropriate treatment plan. We offer an at-home testosterone lab kit to kickstart treatment. 

Our compounded treatment Strut Mojo combines enclomiphene with the option of adding tadalafil (generic Cialis) in an easy once-daily oral capsule. 

Getting started is easy:

1. Complete our quick online questionnaire about your symptoms
2. A board-certified physician will review your information and check your lab results to see if your testosterone levels are low
3. If approved, your custom-formulated Strut Mojo will be shipped directly to your door in discreet packaging

Don't settle for living with low testosterone symptoms or treatment options that compromise other aspects of your health. Take the first step toward optimized testosterone levels with a solution designed to work with your body, not against it.

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