
Last Longer. Stay Harder.
Physician-prescribed capsules combining Paroxetine, an SSRI, along with trusted ED ingredients. Choose from simple 2-ingredient formulas up to our full-strength 4-in-1 Max. Taken as needed, with no daily commitment.

ParoxetineRx formulas contain combinations of the following active ingredients:
Paroxetine — Present in all formulas. SSRI that delays ejaculation by regulating serotonin.
Tadalafil — Present in all formulas. PDE5 inhibitor (active ingredient in Cialis) for erection support.
Sildenafil — Max formulas only. PDE5 inhibitor (active ingredient in Viagra) for additional erection support.
Apomorphine — Max formulas only. Dopamine agonist that stimulates arousal and blood flow.

Warning Header: Important Safety Information for ParoxetineRx
Suicidality Warning: Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults.
Key Safety Points:

Disclaimer: The information provided on this page is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions or concerns about your health, please talk to a doctor. Dapoxetine is not FDA-approved in the US, this is an off-label use of this medication.

Looking for Dapoxetine? Here's What You Need to Know.
If you have been researching Dapoxetine for premature ejaculation, you are not alone. It is one of the most searched PE treatments. But Dapoxetine is not FDA approved in the United States, and availability has become increasingly limited.
Why doctors are recommending Paroxetine instead:
Dosing
FDA-approved in U.S.
Clinical use history
Ejaculatory delay
Head-to-head studies
Dosing
Available now
Dapoxetine
No
Limited
Effective
Comparable to Paroxetine
1-2 hours before activity
No
Paroxetine
Yes (for depression/anxiety)
Decades
~8.8x increase over baseline
Comparable or stronger than Dapoxetine
3-4 hrs before activity
Yes
Dapoxetine: No
Paroxetine: Yes (for depression/anxiety)
Dapoxetine: Limited
Paroxetine: Decades
Dapoxetine: Effective
Paroxetine: ~8.8x increase over baseline
Dapoxetine: Comparable to Paroxetine
Paroxetine: Comparable or stronger than Dapoxetine
Dapoxetine: 1-2 hrs before activity
Paroxetine: 3-4 hrs before activity
Dapoxetine: Increasingly limited
Paroxetine: Yes
ParoxetineRx goes further. Our Max formulas combine Paroxetine with Sildenafil, Tadalafil, and Apomorphine in a single capsule, so you can address PE and ED together. Or start simple with our 2-ingredient PE and ED formula.


ParoxetineRx features Paroxetine, an SSRI that regulates serotonin to delay the ejaculatory reflex. Stop worrying about finishing too soon and actually enjoy the moment.
This isn't just a PE treatment. Every ParoxetineRx formula includes ED support — from Tadalafil in our core formulas to the full Sildenafil + Tadalafil + Apomorphine combination in our Max. One capsule handles both problems.
No daily pills. No messy sprays or numbing wipes. Take one capsule 3-4 hours before activity. That's it.
PE and ED create a cycle of anxiety that makes both worse. ParoxetineRx breaks that cycle with a proven medical approach — so you can stop overthinking and start being present.


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Paroxetine 20mg + Tadalafil 20mg
Our PE + ED essentials. Paroxetine for ejaculation delay, Tadalafil for erection support. Simple, effective, affordable.
30-Day Supply
$49
90-Day Supply
$129
150-Day Supply
$189

Paroxetine 40mg + Tadalafil 20mg
Higher-dose Paroxetine for men who need stronger PE support. Same Tadalafil dose for erection support.
30-Day Supply
$69
90-Day Supply
$179
150-Day Supply
$249

Paroxetine 20mg + Sildenafil 60mg + Tadalafil 7.5mg + Apomorphine 2mg
Our full-strength 4-in-1 formula. Paroxetine for PE + three ED ingredients for maximum erection support.
30-Day Supply
$99
90-Day Supply
$249
150-Day Supply
$359

Paroxetine 20mg + Sildenafil 60mg + Tadalafil 7.5mg + Apomorphine 2mg - Double Dose
Same 4-in-1 Max formula, double the supply per dose for men who need it.
30-Day Supply
$139
90-Day Supply
$299
150-Day Supply
$409


Answer a secure health questionnaire from home. Takes about 10 to 15 minutes.
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A U.S.-licensed physician reviews your information to determine if ParoxetineRx is appropriate.
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Approved medication ships directly to your door in unmarked packaging. Free shipping.
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Message our medical team anytime through your secure Strut account.





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ParoxetineRx is a line of physician-prescribed, compounded oral capsules for premature ejaculation and erectile dysfunction. All formulas contain Paroxetine for PE and Tadalafil for ED. Our Max formulas add Sildenafil and Apomorphine for enhanced erection support.

ParoxetineRx and ParoxetineRx Plus are 2-ingredient formulas (Paroxetine + Tadalafil) — Plus has a higher Paroxetine dose (40mg vs 20mg) for stronger PE support. ParoxetineRx Max is our 4-in-1 formula that adds Sildenafil and Apomorphine for maximum ED support. Max Double provides a double dose per capsule.

Both are SSRIs used for PE. Dapoxetine was designed as a fast-acting, on-demand PE treatment (1-2 hours before activity) but is not FDA-approved in the U.S. and has limited availability. Paroxetine is FDA-approved (not for PE, but for depression/anxiety), has decades of safety data, and clinical studies show it produces comparable or stronger ejaculation delay. Paroxetine is taken 3-4 hours before activity.

Yes. A 2014 comparative study found that on-demand Paroxetine and 60mg Dapoxetine produced similar improvements in ejaculatory latency. Meta-analyses have shown Paroxetine produces approximately an 8.8x increase over baseline.

Take one capsule 3-4 hours before expected sexual activity, with or without food. Do not take more than one capsule in 24 hours

PE effects (Paroxetine) may begin within 3-4 hours. ED effects (Sildenafil/Tadalafil) may begin within 30-60 minutes. Individual results vary.

No. ParoxetineRx is designed for as-needed dosing. Your prescribing physician can help determine the right approach for you.

The most common side effects are injection site reactions (redness, mild irritation), joint pain, and mild swelling. These are typically mild and temporary. Serious side effects are rare. Contact your physician if you experience severe swelling, difficulty breathing, or chest tightness. See the safety information for more detailed potential side effects.

Inform your doctor about heart problems, high or low blood pressure, eye conditions, liver or kidney disease, mental health history, seizure history, or if you take MAO inhibitors, nitrates, blood thinners, or other SSRIs.

Avoid alcohol (causes low blood pressure and dizziness with Sildenafil/Tadalafil), grapefruit products, nitrate medications, MAO inhibitors, and other ED medications unless directed by your physician.

Overdose increases risk of severe nausea, vomiting, dizziness, tremor, or erections lasting 4+ hours (priapism). Seek emergency medical attention immediately.

Store in original container at controlled room temperature (68-77 F). Keep out of reach of children and pets.
Our ParoxetineRx therapy is overseen by physician and pharmacist-led teams, with input from experienced sexual health specialists. This treatment is personalized and prescribed for your unique needs.





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Our formula was developed by leading physicians and compounding pharmacists with decades of experience in sexual health and performance medicine. Strut is qualified to help you find the right treatment for your needs. We are driven to improve the digital healthcare experience and our team is available to help you throughout the process.

ParoxetineRx is a line of physician-prescribed, compounded oral capsules for premature ejaculation and erectile dysfunction. All formulas contain Paroxetine for PE and Tadalafil for ED. Our Max formulas add Sildenafil and Apomorphine for enhanced erection support.
ParoxetineRx and ParoxetineRx Plus are 2-ingredient formulas (Paroxetine + Tadalafil) — Plus has a higher Paroxetine dose (40mg vs 20mg) for stronger PE support. ParoxetineRx Max is our 4-in-1 formula that adds Sildenafil and Apomorphine for maximum ED support. Max Double provides a double dose per capsule.
Both are SSRIs used for PE. Dapoxetine was designed as a fast-acting, on-demand PE treatment (1-2 hours before activity) but is not FDA-approved in the U.S. and has limited availability. Paroxetine is FDA-approved (not for PE, but for depression/anxiety), has decades of safety data, and clinical studies show it produces comparable or stronger ejaculation delay. Paroxetine is taken 3-4 hours before activity.
Yes. A 2014 comparative study found that on-demand Paroxetine and 60mg Dapoxetine produced similar improvements in ejaculatory latency. Meta-analyses have shown Paroxetine produces approximately an 8.8x increase over baseline.
Take one capsule 3-4 hours before expected sexual activity, with or without food. Do not take more than one capsule in 24 hours
PE effects (Paroxetine) may begin within 3-4 hours. ED effects (Sildenafil/Tadalafil) may begin within 30-60 minutes. Individual results vary.
No. ParoxetineRx is designed for as-needed dosing. Your prescribing physician can help determine the right approach for you.
The most common side effects are injection site reactions (redness, mild irritation), joint pain, and mild swelling. These are typically mild and temporary. Serious side effects are rare. Contact your physician if you experience severe swelling, difficulty breathing, or chest tightness. See the safety information for more detailed potential side effects.
Inform your doctor about heart problems, high or low blood pressure, eye conditions, liver or kidney disease, mental health history, seizure history, or if you take MAO inhibitors, nitrates, blood thinners, or other SSRIs.
Avoid alcohol (causes low blood pressure and dizziness with Sildenafil/Tadalafil), grapefruit products, nitrate medications, MAO inhibitors, and other ED medications unless directed by your physician.
Overdose increases risk of severe nausea, vomiting, dizziness, tremor, or erections lasting 4+ hours (priapism). Seek emergency medical attention immediately.
Store in original container at controlled room temperature (68-77 F). Keep out of reach of children and pets.
We mail you a convenient at-home lab test or you can upload your results if you have them. The results establish your baseline for tracking testosterone improvements and customizing your treatment plan.
