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ParoxetineRx

Prescription PE & ED Formulas

Physician-prescribed capsules combining Paroxetine, an SSRI, along with trusted ED ingredients. Choose from simple 2-ingredient formulas up to our full-strength 4-in-1 Max. Taken as needed, with no daily commitment.

Ingredients

ParoxetineRx formulas contain combinations of the following active ingredients:

Paroxetine — Present in all formulas. SSRI that delays ejaculation by regulating serotonin.

Tadalafil — Present in all formulas. PDE5 inhibitor (active ingredient in Cialis) for erection support.

Sildenafil — Max formulas only. PDE5 inhibitor (active ingredient in Viagra) for additional erection support.

Apomorphine — Max formulas only. Dopamine agonist that stimulates arousal and blood flow.

Safety Info

Warning Header: Important Safety Information for ParoxetineRx

Suicidality Warning: Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults.

Key Safety Points:

  • Do not take if you are also using a nitrate drug for chest pain
  • Contact your doctor if erection lasts longer than 4 hours
  • Do not use if allergic to Sildenafil, Tadalafil, or SSRIs

Disclaimer

Disclaimer: The information provided on this page is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions or concerns about your health, please talk to a doctor. Dapoxetine is not FDA-approved in the US, this is an off-label use of this medication.

Get StartedSee if Treatment is Right for Me
Compounded in the U.S.A.
Prescribed by U.S. doctors

Looking for Dapoxetine? Here's What You Need to Know.

If you have been researching Dapoxetine for premature ejaculation, you are not alone. It is one of the most searched PE treatments. But Dapoxetine is not FDA approved in the United States, and availability has become increasingly limited.

Why doctors are recommending Paroxetine instead:

Dosing

FDA-approved in U.S.

Clinical use history

Ejaculatory delay

Head-to-head studies

Dosing

Available now

Dapoxetine

No

Limited

Effective

Comparable to Paroxetine

1-2 hours before activity

No

Paroxetine

Yes (for depression/anxiety)

Decades

~8.8x increase over baseline

Comparable or stronger than Dapoxetine

3-4 hrs before activity

Yes

FDA-approved in U.S.

Dapoxetine: No

Paroxetine: Yes (for depression/anxiety)

Clinical use history

Dapoxetine: Limited

Paroxetine: Decades

Ejaculatory delay

Dapoxetine: Effective

Paroxetine: ~8.8x increase over baseline

Head-to-head studies

Dapoxetine: Comparable to Paroxetine

Paroxetine: Comparable or stronger than Dapoxetine

Dosing

Dapoxetine: 1-2 hrs before activity

Paroxetine: 3-4 hrs before activity

Available now

Dapoxetine: Increasingly limited

Paroxetine: Yes

ParoxetineRx goes further. Our Max formulas combine Paroxetine with Sildenafil, Tadalafil, and Apomorphine in a single capsule, so you can address PE and ED together. Or start simple with our 2-ingredient PE and ED formula.

One Capsule. PE + ED Handled.

No sprays, no wipes, no injections
Just an oral capsule.
As-needed dosing
Take 3-4 hours before activity, no daily regimen.
SimplePE + ED in 
a single capsule
Every formula addresses both issues, from our simple 2-ingredient to our full-strength 4-in-1 Max.
Clinically proven ejaculation delay
Paroxetine produced an ~8.8x increase in ejaculatory latency in clinical studies.

The Science Behind 
Each Ingredient

ParoxetineRx formulas contain combinations of the following active ingredients:

Paroxetine

Ejaculation Delay

all formulas
An SSRI that regulates serotonin reuptake in the brain, delaying the ejaculatory reflex. Clinically studied for PE with an ~8.8x increase in ejaculatory latency. FDA-approved for depression/anxiety; used off-label for PE with decades of safety data.

Sildenafil

Erection Support

max formulas
PDE5 inhibitor (active ingredient in Viagra). Relaxes blood vessels and smooth muscles in the penis to achieve and maintain erections. Onset within 30-60 minutes.

Tadalafil

Erection support

all formulas
PDE5 inhibitor (active ingredient in Cialis). Provides erection support lasting up to 36 hours — the longest-acting ED ingredient available.

Apomorphine

Arousal Support

max formulas
Dopamine agonist that works in the brain to stimulate arousal and increase blood flow to the penis. Complements Sildenafil and Tadalafil for more complete ED support.

What
ParoxetineRx 

Does for You

Get Started Today
Last Longer

ParoxetineRx features Paroxetine, an SSRI that regulates serotonin to delay the ejaculatory reflex. Stop worrying about finishing too soon and actually enjoy the moment.

Stay Harder

This isn't just a PE treatment. Every ParoxetineRx formula includes ED support — from Tadalafil in our core formulas to the full Sildenafil + Tadalafil + Apomorphine combination in our Max. One capsule handles both problems.

Take It When You Need It

No daily pills. No messy sprays or numbing wipes. Take one capsule 3-4 hours before activity. That's it.

Feel Like Yourself Again

PE and ED create a cycle of anxiety that makes both worse. ParoxetineRx breaks that cycle with a proven medical approach — so you can stop overthinking and start being present.

How It Works

Targets PE at the Source
Unlike numbing sprays or topical wipes that reduce sensation, Paroxetine works systemically — regulating serotonin levels in the brain to delay the ejaculatory reflex at its origin. You keep full sensation while lasting longer.
Supports Stronger Erections
All ParoxetineRx formulas include Tadalafil (the active ingredient in Cialis) for erection support. Our Max formulas add Sildenafil (Viagra) and Apomorphine — three ED mechanisms working together for maximum erection support.
Clinically Studied Results
In clinical studies, Paroxetine produced an approximately 8.8-fold increase in ejaculatory latency over baseline. A 2014 comparative study found that on-demand Paroxetine produced similar improvements to 60mg Dapoxetine.

Choose Your Formula

Paroxetine 20mg + Tadalafil 20mg


ParoxetineRx

Our PE + ED essentials. Paroxetine for ejaculation delay, Tadalafil for erection support. Simple, effective, affordable.

30-Day 
Supply

$49

90-Day 
Supply

$129

150-Day 
Supply

$189

Paroxetine 40mg + Tadalafil 20mg


ParoxetineRx Plus

Higher-dose Paroxetine for men who need stronger PE support. Same Tadalafil dose for erection support.

30-Day 
Supply

$69

90-Day 
Supply

$179

150-Day 
Supply

$249

Paroxetine 20mg + Sildenafil 60mg + Tadalafil 7.5mg + Apomorphine 2mg

ParoxetineRx Max

Our full-strength 4-in-1 formula. Paroxetine for PE + three ED ingredients for maximum erection support.

30-Day 
Supply

$99

90-Day 
Supply

$249

150-Day 
Supply

$359

Paroxetine 20mg + Sildenafil 60mg + Tadalafil 7.5mg + Apomorphine 2mg - Double Dose

ParoxetineRx Max Double

Same 4-in-1 Max formula, double the supply per dose for men who need it.


30-Day 
Supply

$139

90-Day 
Supply

$299

150-Day 
Supply

$409

How to Get Started

Complete Your Online Visit

Answer a secure health questionnaire from home. Takes about 10 to 15 minutes.

Physician Review

A U.S.-licensed physician reviews your information to determine if ParoxetineRx is appropriate.

Discreet Shippping

Approved medication ships directly to your door in unmarked packaging. Free shipping.

Ongoing Support

Message our medical team anytime through your secure Strut account.

Get Started
In Stock

ParoxetineRx

Prescription PE & ED Formulas
Fast-acting formula works in as little as 15 minutes
Active for up to 36 hours
No pills to swallow - convenient dissolvable
mint-flavored tablet
Comprehensive 4-in-1 approach targets both physical and mental aspects

Low Strength

TADALAFIL 15MG + OXYTOCIN 100IU +
APOMORPHINE 2MG + VARDENAFIL 5MG

Medium Strength

TADALAFIL 21MG + OXYTOCIN 100IU +
APOMORPHINE 2MG + VARDENAFIL 10MG

High Strength

TADALAFIL 22MG + OXYTOCIN 200IU +
APOMORPHINE 3MG + VARDENAFIL 15MG
Free shipping
Free follow-up care
Cancel anytime,
Free online MD visit

Frequently Asked
Questions

What is ParoxetineRx?

ParoxetineRx is a line of physician-prescribed, compounded oral capsules for premature ejaculation and erectile dysfunction. All formulas contain Paroxetine for PE and Tadalafil for ED. Our Max formulas add Sildenafil and Apomorphine for enhanced erection support.

What's the difference between the formulas?

ParoxetineRx and ParoxetineRx Plus are 2-ingredient formulas (Paroxetine + Tadalafil) — Plus has a higher Paroxetine dose (40mg vs 20mg) for stronger PE support. ParoxetineRx Max is our 4-in-1 formula that adds Sildenafil and Apomorphine for maximum ED support. Max Double provides a double dose per capsule.

How is Paroxetine different from Dapoxetine?

Both are SSRIs used for PE. Dapoxetine was designed as a fast-acting, on-demand PE treatment (1-2 hours before activity) but is not FDA-approved in the U.S. and has limited availability. Paroxetine is FDA-approved (not for PE, but for depression/anxiety), has decades of safety data, and clinical studies show it produces comparable or stronger ejaculation delay. Paroxetine is taken 3-4 hours before activity.

Is Paroxetine as effective as Dapoxetine for PE?

Yes. A 2014 comparative study found that on-demand Paroxetine and 60mg Dapoxetine produced similar improvements in ejaculatory latency. Meta-analyses have shown Paroxetine produces approximately an 8.8x increase over baseline.

How do I take ParoxetineRx?

Take one capsule 3-4 hours before expected sexual activity, with or without food. Do not take more than one capsule in 24 hours

How long does it take to work?

PE effects (Paroxetine) may begin within 3-4 hours. ED effects (Sildenafil/Tadalafil) may begin within 30-60 minutes. Individual results vary.

Do I need to take it every day?

No. ParoxetineRx is designed for as-needed dosing. Your prescribing physician can help determine the right approach for you.

What are the side effects?

The most common side effects are injection site reactions (redness, mild irritation), joint pain, and mild swelling. These are typically mild and temporary. Serious side effects are rare. Contact your physician if you experience severe swelling, difficulty breathing, or chest tightness. See the safety information for more detailed potential side effects.

What should I tell my doctor before starting?

Inform your doctor about heart problems, high or low blood pressure, eye conditions, liver or kidney disease, mental health history, seizure history, or if you take MAO inhibitors, nitrates, blood thinners, or other SSRIs.

What should I avoid while taking ParoxetineRx?

Avoid alcohol (causes low blood pressure and dizziness with Sildenafil/Tadalafil), grapefruit products, nitrate medications, MAO inhibitors, and other ED medications unless directed by your physician.

What if I take too much?

Overdose increases risk of severe nausea, vomiting, dizziness, tremor, or erections lasting 4+ hours (priapism). Seek emergency medical attention immediately.

How should I store it?

Store in original container at controlled room temperature (68-77 F). Keep out of reach of children and pets.

Disclaimer: The information provided on this page is not a substitute for professional medical advice, diagnosis, or treatment. If you have questions or concerns about your health, please talk to a doctor. Paroxetine is FDA-approved for depression and anxiety; its use for premature ejaculation is off-label.

Trust Our Experts

Our ParoxetineRx therapy is overseen by physician and pharmacist-led teams, with input from experienced sexual health specialists. This treatment is personalized and prescribed for your unique needs.

U.S. Licensed & Board Certified Physicians
U.S Pharmacy 
& Medicines
Discreet & Free Shipping
LegitScript Accredited
Get Started

Core Benefits

Enhanced blood flow
for stronger erections

Experience better circulation for more powerful and sustained erections.

Improved arousal
response and sensitivity

Feel heightened sensitivity and a quicker, more intense arousal response.

Extended duration
for up to 36 hours

Enjoy long-lasting performance with effects that can last up to 36 hours.

Boosted confidence 
and performance

Feel more confident in the moment, knowing you’re ready for peak performance.

Super Strut: The Ultimate 4-in-1  ED Tablet

Maximize your performance with our comprehensive formula. 
Our exclusive formula addresses all aspects of sexual performance in one convenient rapid dissolve tablet.

Vardenafil

Active ingredient in Levitra® - Strong and fast acting erectile dysfunction treatment

Oxytocin

The "Love hormone” for potential libido improvements
No fancy packaging. Just hardcore results at a much lower price.

Tadalafil

Active ingredient in Cialis® - Provides extended effectiveness for up to 36 hours

Apomorphine

Primes the brain for arousal and enhanced sensitivity

Apomorphine

Apomorphine: Primes the brain for arousal and enhanced sensitivity

Tadalafil

Active ingredient in Cialis® - Provides extended effectiveness for up to 36 hours

Vardenafil

Active ingredient in Levitra® - Strong and fast acting erectile dysfunction treatment

Oxytocin

The "Love hormone” for potential libido improvements
No fancy packaging. Just hardcore results at a much lower price.

Three-step process

Fill out medical questionnaire
Brief health assessment to customize your treatment plan.
Get custom treatment plan
Our physicians develop a personalized solution just for you.
Shipped directly to your door
Discreet packaging with regular monthly delivery.

Super Strut vs. Traditional ED Solutions

Fast onset
(15 min)
Long duration
(36 hrs)
Targets physical
& mental factors
Easy
administration
No pills to
swallow
Dissolvable
tablet
Comprehensive
4-in-1 formula
Super Strut
Yes
Yes
Yes
Always
Yes
Yes
Yes
Traditional Pills
Varies
Varies
No
Yes
No
No
No
Injections
No
No
No
No
No
No
No

Backed by Science & Experts

Our formula was developed by leading physicians and compounding pharmacists with decades of experience in sexual health and performance medicine. Strut is qualified to help you find the right treatment for your needs. We are driven to improve the digital healthcare experience and our team is available to help you throughout the process.

Safety Information:
All ingredients thoroughly researched and tested for safety. Formulated and compounded in pharmacy board-certified facilities.
"What sets Super Strut apart is our exclusive 4-in-1 formula, designed to address both the physical and mental aspects of erectile dysfunction. Each ingredient has been carefully selected and dosed to provide fast-acting, long-lasting results for enhanced performance, confidence, and satisfaction."
Simal Patel, MD,
Founder & CEO at Strut Health

Frequently asked questions

What is ParoxetineRx?

ParoxetineRx is a line of physician-prescribed, compounded oral capsules for premature ejaculation and erectile dysfunction. All formulas contain Paroxetine for PE and Tadalafil for ED. Our Max formulas add Sildenafil and Apomorphine for enhanced erection support.

What's the difference between the formulas?

ParoxetineRx and ParoxetineRx Plus are 2-ingredient formulas (Paroxetine + Tadalafil) — Plus has a higher Paroxetine dose (40mg vs 20mg) for stronger PE support. ParoxetineRx Max is our 4-in-1 formula that adds Sildenafil and Apomorphine for maximum ED support. Max Double provides a double dose per capsule.

How is Paroxetine different from Dapoxetine?

Both are SSRIs used for PE. Dapoxetine was designed as a fast-acting, on-demand PE treatment (1-2 hours before activity) but is not FDA-approved in the U.S. and has limited availability. Paroxetine is FDA-approved (not for PE, but for depression/anxiety), has decades of safety data, and clinical studies show it produces comparable or stronger ejaculation delay. Paroxetine is taken 3-4 hours before activity.

Is Paroxetine as effective as Dapoxetine for PE?

Yes. A 2014 comparative study found that on-demand Paroxetine and 60mg Dapoxetine produced similar improvements in ejaculatory latency. Meta-analyses have shown Paroxetine produces approximately an 8.8x increase over baseline.

How do I take ParoxetineRx?

Take one capsule 3-4 hours before expected sexual activity, with or without food. Do not take more than one capsule in 24 hours

How long does it take to work?

PE effects (Paroxetine) may begin within 3-4 hours. ED effects (Sildenafil/Tadalafil) may begin within 30-60 minutes. Individual results vary.

Do I need to take it every day?

No. ParoxetineRx is designed for as-needed dosing. Your prescribing physician can help determine the right approach for you.

What are the side effects?

The most common side effects are injection site reactions (redness, mild irritation), joint pain, and mild swelling. These are typically mild and temporary. Serious side effects are rare. Contact your physician if you experience severe swelling, difficulty breathing, or chest tightness. See the safety information for more detailed potential side effects.

What should I tell my doctor before starting?

Inform your doctor about heart problems, high or low blood pressure, eye conditions, liver or kidney disease, mental health history, seizure history, or if you take MAO inhibitors, nitrates, blood thinners, or other SSRIs.

What should I avoid while taking ParoxetineRx?

Avoid alcohol (causes low blood pressure and dizziness with Sildenafil/Tadalafil), grapefruit products, nitrate medications, MAO inhibitors, and other ED medications unless directed by your physician.

What if I take too much?

Overdose increases risk of severe nausea, vomiting, dizziness, tremor, or erections lasting 4+ hours (priapism). Seek emergency medical attention immediately.

How should I store it?

Store in original container at controlled room temperature (68-77 F). Keep out of reach of children and pets.

Easy at home lab test

We mail you a convenient at-home lab test or you can upload your results if you have them. The results establish your baseline for tracking testosterone improvements and customizing your treatment plan.

Learn More