NAD+ Dosing Schedule: How Should I Use My NAD+ Injection?

NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme that plays an essential role in cellular energy production, mitochondrial function, and overall wellness. When used as a subcutaneous injection, it's important to follow the recommended dosing schedule—particularly during your first month, to ensure safe and effective results.

Your First Month: The Titration Phase

During your initial month of treatment, you'll gradually increase your dose. This stepwise approach allows your body to adjust to NAD+ and helps reduce potential side effects like nausea, cramping, or fatigue. Your Strut provider may personalize this schedule based on your specific needs.

Option 1: Twice-Weekly Injections

• Week 1: 0.1 mL (20 mg)
• Week 2: 0.2 mL (40 mg)
• Week 3 and Beyond (Maintenance): 0.6 mL (120 mg)

Option 2: Three-Times-Weekly Injections

• Week 1: 0.1 mL (20 mg)
• Week 2: 0.2 mL (40 mg)
• Week 3 and Beyond (Maintenance): 0.4 mL (80 mg)

Helpful Tip: If you're injecting three times per week, aim for every-other-day dosing (for example, Monday, Wednesday, and Friday). Some flexibility is okay, but try to avoid injecting on consecutive days.

Keep in Mind: The titration schedule applies only to your first month. When you receive refills, they'll contain your full maintenance dose, even if the label still mentions titration.

Refills: Jump Right to Your Maintenance Dose

Once you've completed your initial titration month:

• Begin injecting at your full maintenance dose right away. There's no need to taper up again.
• Common maintenance schedules include:
  • 0.6 mL twice per week
  • 0.4 mL three times per week
• If your refill vial label still shows titration instructions, that's just a pharmacy default, not a sign to repeat the titration process.

Quick Dosing Reference

• 0.1 mL = 20 mg NAD+

Following your prescribed NAD+ dosing schedule helps you get the most from your treatment while supporting your body's natural adjustment process. If you have questions about your specific regimen, your Strut healthcare provider is here to help.

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