Considering NAD+ injections, but not sure what to budget? The answer depends largely on where you get treated—and how often. NAD+ isn't a one-and-done intervention. To maintain benefits like improved energy, sharper cognition, and cellular resilience, most protocols require ongoing treatment, which means the cost structure matters more than the price of a single shot.

At wellness clinics, NAD+ injections typically run $95–$200 per session, with premium locations in major cities often at the higher end. 

That might seem manageable until you realize consistent treatment means multiple visits per month. Weekly protocols put you at $380–$800 monthly, plus the time cost of appointments, travel, and schedule coordination. For a therapy designed to optimize your biology, the logistics can become a friction point.

There's another route. At-home NAD+ injections, starting at $150 per month for a full month supply: same pharmaceutical-grade compound, real physician oversight, none of the clinic overhead or geographical price inflation. 

Let’s explore everything you should know about NAD+ injections cost and how the long-term economics and quality compare.

What Are NAD+ Injections?

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every cell, essential for converting nutrients into cellular energy and activating proteins that regulate DNA repair. 

Why is everyone getting them these days? It’s an anti-aging strategy. NAD+ levels decline significantly with age—by some estimates, dropping roughly 50% between ages 40 and 60. This depletion correlates with fatigue, cognitive decline, and diminished metabolic function–everything we associate with aging slowdown.

Why injection vs. oral supplements

NAD+ injections deliver the compound directly into muscle tissue via intramuscular (IM) administration. 

Unlike oral NAD+ supplements, which must survive digestion and liver metabolism, injections provide higher bioavailability and more predictable dosing. The result is a direct increase in circulating NAD+ that cells can immediately utilize for energy production, DNA repair, and sirtuin activation—the longevity pathways that decline as we age.

Common protocols target energy restoration, cognitive sharpness, athletic recovery, and metabolic optimization. 

Medical-grade and oversight matters

NAD+ injections are a medical treatment, not a boutique wellness amenity. 

Pharmaceutical-grade NAD+ requires compounding pharmacy standards, proper dosing oversight, and physician supervision to ensure safety and efficacy. Not all providers operate at this level—a distinction that matters both clinically and economically.

Clinic NAD+ Injection Costs: What to Expect

The per-shot economics

Most reputable wellness clinics charge $95–$200 per NAD+ injection, with pricing heavily influenced by geography. A shot in Manhattan or West Hollywood will cost more than the same treatment in suburban markets. Premium med spas often position NAD+ alongside aesthetic services, which means you're paying for ambiance, not just medicine.

Monthly commitment adds up 

Here's where single-session pricing becomes misleading. Maintenance protocols typically call for weekly or bi-weekly injections to sustain therapeutic NAD+ levels. Run the numbers:

• Weekly dosing: 4 shots/month = $380–$800
• Bi-weekly dosing: 2 shots/month = $190–$400

That's before factoring in the time cost—scheduling appointments around clinic hours, commuting, waiting rooms, and the inevitable rebooking when they're sold out or your schedule shifts.

At-Home NAD+ Injections: Cost & Convenience

The pricing model

Physician-supervised at-home NAD+ starts at $150 per month through services like Strut Health. That monthly fee includes a full treatment supply: a 500–1000mg vial of pharmaceutical-grade NAD+, compounded in a U.S. pharmacy and prescribed by a U.S.-licensed physician based on your specific health profile. Dosing is customized to your protocol, not a one-size-fits-all standard. The cost also covers your initial medical consultation and any follow-up care, no surprise fees for check-ins or dosing adjustments.

Compare that to clinic economics. 

Even at the conservative end—$95 per shot, twice monthly—you're at $190 for less NAD+ and zero flexibility. Weekly protocols at metro pricing? You're spending 2.5 to 5 times more for the same therapeutic outcome.

Real physician oversight

There’s also a clinical differentiator: at-home NAD+ through a legitimate telemedicine platform isn't a workaround to avoid doctors—it's a model that puts physician supervision at the center. 

You complete a medical assessment. A licensed doctor reviews your health history, contraindications, and treatment goals. If approved, your prescription is filled by a compounding pharmacy that adheres to strict compounding standards, and then ships directly to you.

This isn't a nurse at a med spa following a laminated protocol. It's individualized medicine with ongoing access to your prescribing physician for dosing adjustments, side effect management, or questions. 

Logistics that actually work so you can stay consistent

No appointments. No commute. You administer on your schedule— whenever your protocol calls for it. Injections are subcutaneous or intramuscular, straightforward enough that most people are comfortable after the first attempt. 

Consistency matters with NAD+ therapy. And the at-home model removes every friction point that causes people to miss doses or abandon treatment altogether because the logistics become unsustainable.

Clinic vs. At-Home: Direct NAD+ Injection Cost Comparison

Monthly cost breakdown

The 6-month NAD+ injection cost outlook

Let's consider NAD+ injection cost for over half a year of consistent treatment:

• Clinic route: $2,280–$4,800 (plus commute time, schedule juggling, potential gaps in supply)
• At-home route: $900 (plus zero logistical friction)

That's a $1,380–$3,900 difference for the same therapeutic compound, often with superior medical oversight. The cost gap isn't about cutting corners—it's about cutting inefficiency.

Summary: NAD+ Injection Cost 

NAD+ injection cost at wellness clinics runs $95–$200 per shot, translating to $380–$800 monthly for standard weekly protocols. 

Physician-supervised at-home NAD+ starts at $150 per month for a full treatment supply—pharmaceutical-grade, U.S.-compounded, with medical consultation and follow-up care included. 

Over six months of consistent treatment, you're looking at $2,280–$4,800 for clinic visits versus $900 for at-home delivery. Same therapeutic compound, physician oversight, and a significantly lower cost. 

Want to see if at-home NAD+ therapy is right for you?

Learn more about how NAD+ can support your energy, focus, and longevity goals. Strut Health offers physician-formulated NAD+ injectables designed for convenience and consistency.

Here's how it works:

Complete a 5-minute medical assessment. A U.S.-licensed physician reviews your health profile and treatment goals. If approved, your custom NAD+ treatment—pharmaceutical-grade NAD+ compounded specifically for you—ships discreetly to your door. Ongoing support is included as you dial in your protocol.

Starting at $150/month for pharmaceutical-grade NAD+ with real medical oversight and follow-up care.

See if you qualify →