How Much Does Enclomiphene Raise Testosterone?

If you've been researching treatments for low testosterone, you've likely come across enclomiphene citrate. This medication has gained attention as an alternative to traditional testosterone replacement therapy, particularly for men who want to maintain their fertility. 

But how much does enclomiphene raise testosterone? Let's dive into what the research tells us.

What Is Enclomiphene?

Enclomiphene citrate is a selective estrogen receptor modulator (SERM) that's used off-label to treat low testosterone in men. 

Unlike synthetic testosterone gel or injections that directly replace the hormone, enclomiphene works by stimulating your body's natural testosterone production. 

How Does Enclomiphene Work?

Think of enclomiphene as a messenger that tells your body to make more testosterone naturally. Here's the simplified process:

1. Blocks estrogen signals: Enclomiphene blocks estrogen receptors in your brain, specifically in the hypothalamus and pituitary gland
2. Triggers hormone release: This blocking action tricks your brain into thinking testosterone levels are low
3. Stimulates natural production: Your pituitary gland responds by releasing hormones (LH and FSH) that signal your testicles to produce more testosterone
4. Maintain fertility: Unlike direct testosterone replacement, this process may be more likely to keep your sperm production intact

How Much Does Enclomiphene Raise Testosterone? The Research

Study 1: Significant Testosterone Increases (2013)

A 2013 study followed men with low testosterone levels (below 350 ng/dL) and found impressive results. After treatment with enclomiphene, participants saw their average testosterone levels jump to 604 ng/dL – that's a substantial increase that brought most men well into the normal testosterone range.

Study 2: Comparing Enclomiphene to Testosterone Gel (2015)

A larger 2015 study provided even more detailed insights. Researchers followed 265 men with low testosterone for 16 weeks, comparing different treatments:

• 12.5mg enclomiphene daily
• 25mg enclomiphene daily
• Testosterone gel daily

The Results:

All participants started with testosterone levels below 300 ng/dL – within the low testosterone range. 

Within just 4 weeks of starting enclomiphene, testosterone levels reached a steady state above 400 ng/dL, with the average climbing to around 450 ng/dL.

These elevated levels weren't just a temporary spike – they remained consistently high throughout the entire 16-week study period.

The Big Advantage: Fertility Preservation

Here's where enclomiphene really shines compared to traditional testosterone replacement. 

In the same 2015 study:

• Testosterone gel users: Saw their sperm counts decrease (a common side effect of direct testosterone replacement)
• Enclomiphene users: Maintained healthy sperm counts while achieving similar testosterone increases

This makes enclomiphene particularly attractive for men who want to treat low testosterone but still maintain their fertility.

What Do These Numbers Mean in Real Terms?

Let’s put these results in perspective to understand just how much does enclomiphene raise testosterone:

• Normal testosterone range: Generally 300-1,000 ng/dL (varies)
• Low testosterone: Typically below 300 ng/dL
• Study participants' starting levels: Below 300-350 ng/dL
• Results with enclomiphene: 450-604 ng/dL average

This means enclomiphene helped move men from clearly deficient levels into the healthy, normal range – roughly a 50-100% increase in many cases.

Important Considerations

While these studies show promising results, it's crucial to remember:

Individual results vary: Not everyone will see the same degree of improvement

Medical supervision required: Enclomiphene should only be used under proper medical guidance

Ongoing monitoring needed: Regular blood tests are essential to track progress and adjust treatment

Not for everyone: Some men may not respond as well to enclomiphene compared to direct testosterone replacement. And, enclomiphene should only be used in men who have existing low testosterone levels.

Bottom Line: How Much Does Enclomiphene Raise Testosterone? 

Research demonstrates that enclomiphene might effectively raise testosterone levels by 50-100% or more in men with low testosterone, typically bringing levels from the deficient range (below 300 ng/dL) into the normal, healthy range (400-600+ ng/dL). 

The added benefit of maintaining fertility makes it an attractive option for many men dealing with low testosterone, who still want the option of starting a family in the near-ish future.

If you're considering enclomiphene for low testosterone, discuss these findings with your healthcare provider to determine if it might be right for your specific situation. They can evaluate your current hormone levels, health status, and treatment goals to create the best plan for you.

Getting Enclomiphene Treatment Online with Strut Health

If you're interested in exploring enclomiphene as a treatment option for low testosterone, Strut Health offers convenient online consultations with licensed healthcare providers. 

Ready to take the next step? Visit Strut Health to start your online consultation and discover if enclomiphene could be the right solution for your low testosterone concerns.

‍