How Does Viagra (Sildenafil) Work?: 6 Steps Happening in Your Body From Pill to Pillow

Everyone knows that Viagra, or its generic form Sildenafil, helps you have an erection after you take it, but what are the steps in between?

We think that everyone should know at least a little bit of the science behind what makes their medications do what they do.

Plus - it’s a pretty interesting and ingenious mechanism.

In this article, we will delve into what exactly is happening in your body in six steps to produce Viagra’s effect.

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Step 1: You take your tablet.

The first step is to take your Viagra, or generic form Sertraline, by mouth with some water.

The tablet will then start dissolving in your stomach and start to make its way into your bloodstream.

Pro tip: Taking Viagra with food, especially a high-fat meal, may decrease the amount that is able to get into your body a bit, so an empty stomach may yield better results.

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Step 2: Viagra binds to PDE5 in your body.

Once the Viagra is in your system, it goes around the body with one mission: It wants to find all of your PDE5 (Phosphodiesterase 5) enzymes and temporarily disable them.

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PDE5 is an enzyme that the penis has a lot of, and it normally has the job of breaking down a chemical (cGMP) that makes blood vessels open up.

So, about 30-60minutes after taking your pill, Viagra is stuck onto these PDE5 enzymes and makes them not able to work.

This sets the stage for you to come in.

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Step 3: You get “in the mood.”

During this next step, you are probably with your partner and your brain becomes mentally stimulated.

This leads to your brain sending signals to the nerves located in your penis and signals the release of lots of molecules called Nitric Oxide (NO).

Side note: The way that Viagra works, it is necessary for a mental stimulus to start these steps. So, if you are not properly mentally stimulated, the rest of the steps might not happen.

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Step 4: NO signals cGMP to be made.

When Nitric Oxide is around in the penis, it signals the cells to make lots of cGMP (Cyclic Guanosine Monophosphate).

The job of cGMP is to relax the smooth muscles lining the blood vessels in the area.

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Step 5: cGMP increases the blood flow to the area.

Now that there is a lot of cGMP produced, the vessels in the penis are signaled to open up and let a lot of blood in.

This relaxing of the vessels leads to increased blood flow to the area and produces an erection as long as the cGMP is around.

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Step 6: cGMP sticks around longer than usual.

Normally, the cGMP that is letting in all of the blood is very quickly destroyed by all the PDE5 floating around.

Without this large amount of cGMP around, the vessels usually quickly narrow again and reduce any additional blood flow to the penis.

But, with Viagra, you have the PDE5 all tied up and unable to go about its usual breakdown duties.

This means that cGMP is able to hang out a lot longer than it usually does, leading to more blood flow kept in the area for a longer amount of time than usual.

And, for most guys, this means longer and firmer erections.

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Summary

Basically - Viagra gums up PDE5 enzyme for a while so all the blood flow molecules can do their thing for a lot longer than usual.

Now that you know the science behind what makes Viagra, or Sildenafil, work so well, you may be better able to time out and control your dose.

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If you are interested in trying out Sildenafil, the generic form of Viagra, you can schedule an Online Appointment with our physicians today at StrutYours.com.

If generic Viagra is a good choice for you, we can ship your prescription directly and discreetly to your front door.