Disclaimer: The information provided on this page is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions or concerns about your health, please talk to a doctor.
Tadalafil is a PDE5 inhibitor that is most commonly used for erectile dysfunction or ED. Tadalafil is the active ingredient in Cialis. Tadalafil is in the same class of medications as Viagra (Sildenafil), Levitra (Vardenafil), and Stendra (Avanafil). These medications may have slight differences in effect, and your doctor may choose one over the other based on your treatment goals.
Tadalafil is the generic form of Cialis. Generic medications are required by the FDA to be bioequivalent to the brand medication, meaning that they act the same way in the body and have the same active ingredients. Generic medications also tend to be less expensive than the brand medications and most medications sold in the U.S. are generic.
To get an erection, the body uses chemical signals that tell the vessels to open up and flood blood into the penis when mentally stimulated. Normally, the body then almost as quickly uses an enzyme (PDE-5) to break down those blood flow chemicals, causing blood to leave and the erection to go down. Tadalafil works by blocking the breakdown enzyme (PDE-5), to help maintain the blood flow and erection.
Take the dose directed by your doctor by mouth with some water.You may be able to have sexual activity 30 minutes after taking Tadalafil and up to 36 hours after taking your dose. This extended duration of Tadalafil is why this medication is sometimes referred to as “the weekend pill.” Do not take more than one dose daily. You may take your dose on an empty stomach or with food. Take only the amount of Tadalafil your doctor directed you to take, taking more Tadalafil than directed may cause an increased risk of side effects.
Most patients will start having a response from Tadalafil 30 minutes after taking their dose, although full effects may take longer. Tadalafil may make it easier to achieve an erection for up to 36 hours after taking one dose.
In most people, the effects of Tadalafil can last up to 36 hours. Even after the effects of the medication have worn off, the medication is still in your system for up to a day after dosing - so do not take more than one dose daily. If you find your dose lasting 4+ hours, seek medical attention as this is considered priapism and could have damaging effects on the tissues.
Before taking Tadalafil make sure your doctor knows about any of the following health conditions: Heart conditions, liver, kidney, eye conditions, bleeding disorders, or penile deformities. Also make sure your doctor knows about all of your current medications, supplements, and any other conditions.
Drinking alcohol with Tadalafil can cause side effects including low blood pressure or dizziness. Grapefruit may interact with Tadalafil and lead to unwanted side effects. Avoid the use of grapefruit products. Avoid using any other medicines to treat impotence, such as alprostadil or yohimbine, without first talking to your doctor.
The common side effects of Tadalafil are: headache, indigestion, back pain, muscle aches, flushing, and a stuffy or runny nose. For a full list of possible side effects see the important safety information below.
Taking too much Tadalafil can increase adverse side effects of the medication including severe side effects including extremely low blood pressure or having an erection for longer than 4 hours (priapism). If you have taken more than prescribed by your doctor, or you took the directed amount but you are still having these side effects, seek emergency medical attention.
You should not use tadalafil if you are allergic to it, or:
To make sure tadalafil is safe for you, tell your doctor if you have ever had:
Get emergency medical help if you have signs of an allergic reaction to tadalafil:
Stop taking tadalafil and get emergency medical help if you have:
Common tadalafil side effects may include:
Heart attack, irregular heart beat, stroke, and death have occurred rarely in men taking Cialis. The majority of these men had severe cardiac problems before taking Cialis. It is not known if Cialis caused these problems.This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
The following links provide further information of the potential risks and benefits of this medication: