Learn why using a clindamycin and tretinoin combination cream might be a great addition to your skincare regimen.
Arya Stark and The Hound, Han Solo and Chewbacca, Captain Kirk and Spock.
The most iconic duos work so well together because their differences complement each other and the whole ends up greater than the sum of its parts.
The same is true of Clindamycin plus Tretinoin for acne treatment.
Below, we will explain why Clindamycin with Tretinoin should be your new favorite acne cream collaboration.
Clindamycin is a prescription topical antibiotic that falls into the class of lincomycin antibiotics.
Its main use in the topical form is for acne treatment.
Tretinoin is a prescription-only vitamin A derivative that falls into the Retinoid class of chemicals.
We explained the difference between Tretinoin and the over-the-counter retinoids in our article: Here.
Tretinoin is mainly prescribed for acne, scars, or its anti-aging properties.
Clindamycin alone has been used for acne for over 5 decades.
It works for acne by removing or slowing the growth of the bacteria present on the skin, and significantly reducing skin inflammation.
Clindamycin works great for inflammatory acne (inflamed pimples and pustules).
Tretinoin helps with acne by unclogging pores, promoting a normal sebum flow, and increasing healthy cell turnover.
Tretinoin works best for comedonal acne (blackheads and whiteheads).
We figured out a while ago that Clindamycin is good for acne but recently found that it works even better when in a combination cream.
One study compared Clindamycin alone vs Clindamycin / Tretinoin over the course of 12 weeks.
The combination group saw a significant increase in the acne treatment success scores over Clindamycin alone.
And while Tretinoin is the darling of the derm world, it’s known for its initial irritating properties.
Adding Clindamycin into the mix might help lessen the irritation of Tretinoin used alone.
Also, the combo covers both types of acne:
1. Don’t “spot treat”
2. Make sure the skin is completely dry before applying
3. Applying on top of your moisturizer can reduce irritation
4. A pea-sized amount is plenty
5. Apply at about the same time daily
6. Consistency is key
7. Apply at night
8. Wear sunscreen daily
You can find this combo through prescription only in a Brand name cream called Ziana.
Products that also contain Niacinamide (like our Strut Acne Formula) might help counter tretinoin irritation.
The addition of Niacinamide (Vitamin B3) might also help with inflammation, hydration, and helps smooth out the skin surface structure.
We outlined the full benefits of including Niacinamide Here.