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Learn More About SuperStrut: The Ultimate 4-in-1 ED Treatment

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Our new SuperStrut rapid-dissolve tablets combine 4 active ingredients to help with ED.

SuperStrut 4-in-1 ED Tablets may be a good option for those who want a faster onset or need a stronger formulation than the usual single ingredient ED treatments.

4 active ingredients in 1 treatment:

  • Tadalafil (Generic Cialis)
  • Oxytocin (“love hormone”)
  • PT-141 (peptide for desire)
  • Vitamin D

SuperStrut 4-in-1 ED Tablets may help men reduce erectile dysfunction, improve sexual performance, and boost desire. This medication includes Tadalafil (generic Cialis) which relaxes vessels and smooth muscles in the penile tissue to help achieve and maintain erections more easily. SuperStrut 4-in-1 ED Tablets also include the “love hormone” Oxytocin to boost feelings of connection and intimacy with your partner. By also including peptide PT-141 (Bremelanotide), this medication stimulates the central nervous system to help improve desire, excitement, and arousal. Vitamin D is included as low levels of this vitamin have been associated with erectile dysfunction.

SuperStrut 4-in-1 ED Tablet pricing

SuperStrut 4-in-1 ED Tablets are available in regular strength or maximum strength doses for as low as $5 or $7 per tablet.

How to try SuperStrut 4-in-1 ED Tablets

You can have your free online questionnaire-based consultation through our telemedicine platform at, select your desired dose, and checkout.

If you are a good candidate for SuperStrut 4-in-1 ED Tablets, your medication will be shipped to your front door with our free shipping.

SuperStrut 4-in-1 ED Tablet FAQs

What are SuperStrut 4-in-1 ED Tablets?

SuperStrut 4-in-1 ED Tablets are rapid dissolve tablets that may help men with erectile dysfunction while boosting desire, arousal, excitement, and sexual response. SuperStrut 4-in-1 ED Tablets are prescription 4-in-1 compounded tablets that dissolve quickly under the tongue for rapid absorption into the bloodstream and fast results. The tablet has a pleasant peppermint flavor.

What is Tadalafil?

Tadalafil is a PDE5 inhibitor that is most commonly used for erectile dysfunction (ED). Tadalafil is the active ingredient in Cialis. Tadalafil is in the same class of medications as Viagra (Sildenafil), Levitra (Vardenafil), and Stendra (Avanafil). Tadalafil helps to relax the blood vessels and smooth muscles in the penis to make it easier to achieve and maintain an erection for up to 36 hours.

What is Oxytocin?

Oxytocin, also known as the “love hormone” is a hormone that functions as a neurotransmitter and is naturally made in the hypothalamus portion of the brain. In humans, the release of oxytocin in the body can lead to relationship-enhancing effects including trust, positive relationship memories, positive communication, relaxation, and feeling a stronger bond to your partner.

What is PT-141?

PT-141 (Bremelanotide) is a peptide in the medication class of melanocortin receptor agonists. PT-141 can stimulate neurons in the central nervous system and may help some men with erectile dysfunction see an increase in erectile activity.

Why is Vitamin D included?

There have been associations between low vitamin D levels and the occurrence or severity of erectile dysfunction. Since many people may be low in vitamin D without knowing it, including a moderate amount in this formulation may help reduce vitamin D deficiencies that could negatively affect erectile performance.

How do SuperStrut 4-in-1 ED Tablets work?

The SuperStrut 4-in-1 ED Tablet formula combines Tadalafil, Oxytocin, PT-141, and Vitamin D for a 4-in-1 approach to men’s sexual health issues. Tadalafil works with the vascular system and smooth muscles to improve erectile blood flow. Oxytocin may boost trust, relaxation, and the feelings of a strong intimate connection with your partner while easing performance anxiety. PT-141 works in the central nervous system to help boost erectile activity while potentially boosting desire. Vitamin D is included to help keep levels optimal as low Vitamin D levels have been associated with erectile dysfunction severity.

How should I take SuperStrut 4-in-1 ED Tablets?

Take the dose directed by your doctor by placing the rapid dissolve tablet underneath your tongue and allowing it to dissolve. This may take a minute or two to fully absorb under your tongue and into your cheek tissues. You may be able to have sexual activity 5-30 minutes after taking SuperStrut tablets and up to 36 hours after taking your dose. Do not take more than one dose daily. You may take your dose on an empty stomach or with food. Take only the amount of Tadalafil your doctor directed you to take, taking more Tadalafil than directed may cause an increased risk of side effects.

How should I store this medication?:

Store this medication in the original container in a cool, dry environment, at a controlled room temperature (68F-77F).

How long do SuperStrut 4-in-1 ED Tablets take to work?

Most patients will start having a response from SuperStrut tablets 5-30 minutes after taking their dose, although full effects may take longer. SuperStrut 4-in-1 ED Tablets may make it easier to achieve an erection for up to 36 hours after taking one dose.

How long do SuperStrut 4-in-1 ED Tablets last?

In most people, the effects of SuperStrut tablets can last up to 36 hours. Even after the strongest effects of the medication have worn off, the medication is still in your system for up to a day after dosing - so do not take more than one dose daily. If you find your erection lasting 4+ hours, seek medical attention immediately as this is considered priapism and could have damaging effects on the tissues.

What should I tell my doctor before starting SuperStrut 4-in-1 ED Tablets?

Before taking SuperStrut tablets make sure your doctor knows about any of the following health conditions: High blood pressure, low blood pressure, high levels of vitamin D, high levels of Calcium, heart conditions, liver, kidney, eye conditions, bleeding disorders, an electrolyte imbalance, or penile deformities. Also make sure your doctor knows about all of your current medications, supplements, and any other conditions.

What should I avoid while taking SuperStrut 4-in-1 ED Tablets?

Drinking alcohol with SuperStrut tablets can cause side effects including low blood pressure or dizziness. Grapefruit may interact with SuperStrut tablets and lead to unwanted side effects. Avoid the use of grapefruit products. Avoid using any other medicines to treat impotence, such as alprostadil or yohimbine, or other ED medications without first talking to your doctor. Do not use with any nitrate medications to avoid a sudden and serious drop in blood pressure.

What are the common side effects of SuperStrut 4-in-1 ED Tablets?

The common side effects of Tadalafil are: headache, indigestion, back pain, muscle aches, flushing, and a stuffy or runny nose. 

The potential side effects of Oxytocin are: nausea, vomiting.

The potential side effects of PT-141 are: increased blood pressure, nausea, vomiting, skin flushing, stuffy nose, cough, tiredness, dizziness, or headache.

For a full list of possible side effects see the important safety information.

What if I take too many SuperStrut 4-in-1 ED Tablets?

Taking too many SuperStrut tablets can increase adverse side effects of the medication including severe side effects including extremely low or high blood pressure or having an erection for longer than 4 hours (priapism). If you have taken more than prescribed by your doctor, or you took the directed amount but you are still having these side effects, seek emergency medical attention.

Popular Questions and Related Information:

Important Safety Information for SuperStrut 4-in-1 ED Tablets


  • Do not take if you are also using a nitrate drug for chest pain or heart problems, including nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, and some recreational drugs such as "poppers". Taking tadalafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure.
  • Some medicines can cause unwanted or dangerous effects when used with tadalafil. Tell your doctor about all your current medicines, especially riociguat (Adempas). Do not take tadalafil with riociguat.
  • Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis.

Before taking this medication:

You should not use SuperStrut 4-in-1 ED Tablets if you are allergic to any ingredients, or:

  • If you take medicines to treat pulmonary arterial hypertension, such as riociguat (Adempas).
  • If you are also using a nitrate drug for chest pain or heart problems. This includes nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate. Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite ("poppers"). Taking tadalafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure.

To make sure SuperStrut 4-in-1 ED tablets are safe for you, tell your doctor if you have ever had:

  • Heart problems (chest pain, a heart rhythm disorder, heart attack, heart disease)
  • Pulmonary hypertension
  • High or low blood pressure
  • Previous stroke
  • Blood circulation problems
  • Retinitis pigmentosa (an inherited condition of the eye)
  • Severe vision problems (including NAION)
  • Blindness in one or both eyes
  • Bleeding problems
  • A stomach ulcer
  • Pulmonary veno-occlusive disease (PVOD)
  • Liver or kidney disease or require dialysis
  • A blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia
  • A physical deformity of the penis (such as Peyronie's disease)
  • If you have been told you should not have sexual intercourse for health reasons
  • If you have ever had an erection lasting 4 hours or longer
  • An electrolyte imbalance
  • High levels of vitamin D
  • High levels of Calcium
  • Vascular dysfunction
  • Volume overload

Drug Interactions:

  • Nitrates: Nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, and some recreational drugs such as "poppers". Taking a nitrate medicine with tadalafil can cause a dangerous decrease in blood pressure.
  • Guanylate cyclase stimulators: Adempas® (riociguat)
  • Alpha-blockers: Hytrin® (terazosin HCl), Flomax® (tamsulosin HCl), Cardura® (doxazosin mesylate), Minipress® (prazosin HCl), Uroxatral® (alfuzosin HCl), Jalyn® (dutasteride and tamsulosin HCl), or Rapaflo® (silodosin)
  • HIV protease inhibitors: ritonavir (Norvir®), indinavir sulfate (Crixivan®), saquinavir (Fortovase® or Invirase®), or atazanavir sulfate (Reyataz®)
  • Oral antifungal medicines: ketoconazole (Nizoral®) and itraconazole (Sporanox®)
  • Antibiotics: clarithromycin (Biaxin®), telithromycin (Ketek®), or erythromycin
  • Other medicines that treat high blood pressure
  • Other medicines or treatments for ED
  • Pain medications or Naltrexone
  • Cialis and generic Cialis also contain tadalafil, tadalafil is also found in a drug called Adcirca used for pulmonary arterial hypertension (PAH). Do not use tadalafil with Cialis, Adcirca, or with any other PDE5 inhibitor or erectile dysfunction treatment (sildenafil).
  • PT-141 may slow your digestion and make it take longer for your body to absorb medications taken by mouth.

Side Effects:

Get emergency medical help if you have signs of an allergic reaction:

  • Hives, difficulty breathing, swelling of your face, lips, tongue, or throat.

Stop taking this medication and get emergency medical help if you have:

  • heart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating
  • vision changes or sudden vision loss, blurred vision
  • erection is painful or lasts longer than 4 hours (prolonged erection can damage the penis)
  • ringing in your ears, or sudden hearing loss
  • irregular heartbeat
  • swelling in your hands, ankles, or feet
  • shortness of breath
  • seizure (convulsions)
  • a light-headed feeling, like you might pass out
  • a slow, fast, or uneven heart rate
  • High blood pressure -- severe headache, pounding in your neck and ears
  • confusion, severe weakness, unsteady feeling
  • severe or ongoing nausea
  • Signs of too much vitamin D -- weakness, metallic taste, weight loss, bone or muscle pain, nausea, vomiting, constipation.

Common SuperStrut side effects may include:

  • flushing (warmth, redness, or tingly feeling)
  • headache, tiredness, dizziness
  • heartburn, or upset stomach
  • abnormal vision (blurred vision, changes in color vision, vision with a blue tinge)
  • cough, runny or stuffy nose, nosebleeds
  • rash
  • nausea, vomiting
  • muscle pain, back pain

Heart attack, irregular heartbeat, stroke, and death have occurred rarely in men taking Cialis. The majority of these men had severe cardiac problems before taking Cialis. It is not known if Cialis caused these problems.

PT-141 may darken your gums or skin color. This issue may be more common if you have a darker skin color. Skin changes may be permanent even after stopping PT-141.

This is not a complete list of side effects and others may occur. Talk to your doctor for medical advice about side effects.

Additional Resources

The following links provide further information on the potential risks and benefits of this medication:

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